Antiprotons have been detected in cosmic rays for over 25 years, first by balloon-borne experiments and more recently by satellite-based detectors. The standard picture for their presence in cosmic rays is that they are produced in collisions of cosmic ray protons with nuclei in the interstellar medium, via the reaction, where A represents a nucleus:

The existence of the antiproton with −1 electric charge, opposite to the +1 electric charge of the proton, was predicted by The antiproton was first experimentally confirmed in 1955 at the The antiproton cosmic ray energy spectrum is now measured reliably and is consistent with this standard picture of antiproton production by cosmic ray collisions.The magnitude of properties of the antiproton are predicted by Formation of antiprotons requires energy equivalent to a temperature of 10 trillion Antiprotons have been shown within laboratory experiments to have the potential to treat certain cancers, in a similar method currently used for ion (proton) therapy.

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